use of Soylent Meal Replacement™ as a way to maintain weight during radiation treatment

The purpose of this research study is to assess whether the liquid meal replacement product Soylent™ may reduce the risk of malnutrition and need for g-tube placement during following treatment for head and neck cancer with chemoradiation.  Soylent™ is a liquid meal replacement which is commonly used for nutrition. 

The purpose of this research study is to assess whether the liquid meal replacement product Soylent™ may reduce the risk of ...

The purpose of this research study is to assess whether the liquid meal replacement product Soylent™ may reduce the risk of malnutrition and need for g-tube placement during following treatment for head and neck cancer with chemoradiation.  Soylent™ is a liquid meal replacement which is commonly used for nutrition. 

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the results

1. patients who were prescribed for Soylent meal replacement diets maintained more easily than the counterparts who did not.
2. in addition to maintaining weight, the patients who consumed Soylent also had better reported quality of life.

Valle, L., et al. "Patient-Reported Quality of Life Outcomes After Integrating Exclusive Liquid Meal Replacement in Patients With Head and Neck Cancer Undergoing Chemoradiation: Results From a Phase II Study." International Journal of Radiation Oncology, Biology, Physics 111.3 (2021): e379-e380.

portfolio diet score and risk of cardiovascular disease: findings from 3 prospective cohort studies

The plant-based Portfolio dietary pattern includes recognized cholesterol-lowering foods (i.e., plant protein, nuts, viscous fiber, phytosterols, and plant monounsaturated fats) shown to improve several cardiovascular disease (CVD) risk factors in randomized controlled trials. The primary objective was to examine the relationship between the Portfolio Diet Score (PDS) and the risk of total CVD, coronary heart disease (CHD), and stroke.

The plant-based Portfolio dietary pattern includes recognized cholesterol-lowering foods (i.e., plant protein, nuts, viscous...

The plant-based Portfolio dietary pattern includes recognized cholesterol-lowering foods (i.e., plant protein, nuts, viscous fiber, phytosterols, and plant monounsaturated fats) shown to improve several cardiovascular disease (CVD) risk factors in randomized controlled trials. The primary objective was to examine the relationship between the Portfolio Diet Score (PDS) and the risk of total CVD, coronary heart disease (CHD), and stroke.

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the results

1. the portfolio diet (including Soylent consumption) was correlated with lower risk of cardiovascular disease.
2. it was also linked to a lower cholesterol score and inflammatory profile.

Glenn, Andrea J., et al. "Portfolio Diet Score and Risk of Cardiovascular Disease: Findings From 3 Prospective Cohort Studies." Circulation 148.22 (2023): 1750-1763.

University of California Berkeley

an interventional Soylent diet increases the bacteroidetes to firmicutes ratio in human gut microbiome communities: a randomized controlled trial

Our knowledge of the relationship between the gut microbiome and health has rapidly expanded in recent years. Diet has been shown to have causative effects on microbiome composition, which can have subsequent implications on health. Soylent 2.0 is a liquid meal replacement drink that satisfies nearly 20% of all recommended daily intakes per serving. This study aims to characterize the changes in gut microbiota composition resulting from a short-term Soylent diet.

Our knowledge of the relationship between the gut microbiome and health has rapidly expanded in recent years. Diet has been ...

Our knowledge of the relationship between the gut microbiome and health has rapidly expanded in recent years. Diet has been shown to have causative effects on microbiome composition, which can have subsequent implications on health. Soylent 2.0 is a liquid meal replacement drink that satisfies nearly 20% of all recommended daily intakes per serving. This study aims to characterize the changes in gut microbiota composition resulting from a short-term Soylent diet.

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the results

1. We conclude that a short-term interventional Soylent diet does not negatively impact the composition of gut flora communities, in fact in improves it.
2. Soylent consumption significantly increases the Bacteroidetes to Firmicutes ratio in the gut microbiota.

Hsu, Ryan H., et al. "An interventional Soylent diet increases the Bacteroidetes to Firmicutes ratio in human gut microbiome communities: a randomized controlled trial." bioRxiv (2017): 200881.